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1

Effect of aluminum adjuvant and preservatives on structural integrity and physicochemical stability profiles of three recombinant subunit rotavirus vaccine antigens

Agarwal, Sanjeev, Hickey, John M., McAdams, David, White, Jessica A., Sitrin, Robert, Khandke, Lakshmi, Cryz, Stanley, Joshi, Sangeeta B., Volkin, David B.

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 1.39 MB

english, 2019

2

Analytical lessons learned from selected therapeutic protein drug comparability studies

Federici, Marcia, Lubiniecki, Anthony, Manikwar, Prakash, Volkin, David B.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

3

High-Definition Mapping of Four Spatially Distinct Neutralizing Epitope Clusters on RiVax, a Candidate Ricin Toxin Subunit Vaccine

Toth, Ronald T., Angalakurthi, Siva Krishna, Van Slyke, Greta, Vance, David J., Hickey, John M., Joshi, Sangeeta B., Middaugh, C. Russell, Volkin, David B., Weis, David D., Mantis, Nicholas J., Pasett

Journal:

Clinical and Vaccine Immunology

Year:

2017

Language:

english

File:

PDF, 3.60 MB

english, 2017

4

Effect of aluminum adjuvant and preservatives on structural integrity and physicochemical stability profiles of three recombinant subunit rotavirus vaccine antigens

Agarwal, Sanjeev, Hickey, John M., McAdams, David, White, Jessica A., Sitrin, Robert, Khandke, Lakshmi, Cryz, Stanley, Joshi, Sangeeta B., Volkin, David B.

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

File:

PDF, 1.39 MB

2019

5

Short-term and longer-term protective immune responses generated by subunit vaccination with smallpox A33, B5, L1 or A27 proteins adjuvanted with aluminum hydroxide and CpG in mice challenged with vaccinia virus

Xiao, Yuhong, Zeng, Yuhong, Schante, Carole, Joshi, Sangeeta B., Buchman, George W., Volkin, David B., Middaugh, C. Russell, Isaacs, Stuart N.

Journal:

Year:

2020

File:

PDF, 2.00 MB

2020

6

Disassembly and reassembly of yeast-derived recombinant human papillomavirus virus-like particles (HPV VLPs)

Henryk Mach, David B. Volkin, Robert D. Troutman, Bei Wang, Zheng Luo, Kathrin U. Jansen, Li Shi

Journal:

Journal of Pharmaceutical Sciences

Year:

2006

Language:

english

File:

PDF, 458 KB

english, 2006

7

Protein instability and immunogenicity: Roadblocks to clinical application of injectable protein delivery systems for sustained release

Wim Jiskoot, Theodore W. Randolph, David B. Volkin, C. Russell Middaugh, Christian Schöneich, Gerhard Winter, Wolfgang Friess, Daan J. A. Crommelin, John F. Carpenter

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 103 KB

english, 2012

8

Protein–excipient interactions: Mechanisms and biophysical characterization applied to protein formulation development

Tim J. Kamerzell, Reza Esfandiary, Sangeeta B. Joshi, C. Russell Middaugh, David B. Volkin

Journal:

Advanced Drug Delivery Reviews

Year:

2011

Language:

english

File:

PDF, 2.98 MB

english, 2011

9

Comparability assessments of process and product changes made during development of two different monoclonal antibodies

Anthony Lubiniecki, David B. Volkin, Marcia Federici, Michael D. Bond, Michael L. Nedved, Linda Hendricks, Promod Mehndiratta, Mark Bruner, Sudhir Burman, Paul DalMonte, Jane Kline, Alex Ni, Mark E. P

Journal:

Year:

2011

Language:

english

File:

PDF, 934 KB

english, 2011

10

Properties of ribonucleic acid turnover in T2-infected Escherichia coli

L. Astrachan, E. Volkin

Journal:

Biochimica et Biophysica Acta

Year:

1958

Language:

english

File:

PDF, 591 KB

english, 1958

11

Enhancement of DNA vaccine potency using conventional aluminum adjuvants

J.B. Ulmer, C.M. DeWitt, M. Chastain, A. Friedman, J.J. Donnelly, W.L. McClements, M.J. Caulfield, K.E. Bohannon, D.B. Volkin, R.K. Evans

Journal:

Year:

1999

Language:

english

File:

PDF, 208 KB

english, 1999

12

Effects of Salts from the Hofmeister Series on the Conformational Stability, Aggregation Propensity, and Local Flexibility of an IgG1 Monoclonal Antibody

Majumdar, Ranajoy, Manikwar, Prakash, Hickey, John M., Samra, Hardeep S., Sathish, Hasige A., Bishop, Steven M., Middaugh, C. Russell, Volkin, David B., Weis, David D.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.74 MB

english, 2013

13

Effect of ionic strength and pH on the physical and chemical stability of a monoclonal antibody antigen-binding fragment

Wang, Tingting, Kumru, Ozan S., Yi, Li, Wang, Y. John, Zhang, Jennifer, Kim, Jae Hyun, Joshi, Sangeeta B., Middaugh, C. Russell, Volkin, David B.

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 3.68 MB

english, 2013

14

2053 MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING AND ULTRASOUND FUSION BIOPSY DETECTS PROSTATE CANCER IN PATIENTS WITH PRIOR NEGATIVE TRUS BIOPSIES

Yerram, Nitin, Volkin, Dmitry, Nix, Jeffery, Vourganti, Srinivas, Hoang, An, Ahmed, Faisal, Gupta, Gopal, Rastinehad, Art, Kruecker, Jochen, Kadoury, Sameul, Locklin, Julie, Gates, Stacey, Xu, Sheng,

Journal:

The Journal of Urology

Year:

2012

Language:

english

File:

PDF, 174 KB

english, 2012

15

Probing structurally altered and aggregated states of therapeutically relevant proteins using GroEL coupled to bio-layer interferometry

Naik, Subhashchandra, Kumru, Ozan S., Cullom, Melissa, Telikepalli, Srivalli N., Lindboe, Elizabeth, Roop, Taylor L., Joshi, Sangeeta B., Amin, Divya, Gao, Phillip, Middaugh, C. Russell, Volkin, David

Journal:

Protein Science

Year:

2014

Language:

english

File:

PDF, 1013 KB

english, 2014

16

Calculation of short-pulse propagation in a large CO2-laser amplifier

Volkin, Howard C.

Journal:

Journal of Applied Physics

Year:

1979

Language:

english

File:

PDF, 1.02 MB

english, 1979

17

The Nucleic Acids

Cohn, W E, Volkin, E

Journal:

Annual Review of Biochemistry

Year:

1957

Language:

english

File:

PDF, 1.27 MB

english, 1957

18

An Evaluation of Major Components in a Self-Control Therapy Program for Depression

Rehm, L. P., Kornblith, S. J., O'Hara, M. W., Lamparski, D. M., Romano, Joan. M., Volkin, J. I.

Journal:

Behavior Modification

Year:

1981

Language:

english

File:

PDF, 2.03 MB

english, 1981

19

Physical Characterization and In Vitro Biological Impact of Highly Aggregated Antibodies Separated into Size-Enriched Populations by Fluorescence-Activated Cell Sorting

Telikepalli, Srivalli, Shinogle, Heather E., Thapa, Prem S., Kim, Jae Hyun, Deshpande, Meghana, Jawa, Vibha, Middaugh, C. Russell, Narhi, Linda O., Joubert, Marisa K., Volkin, David B.

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

20

Evaluating the Role of the Air-Solution Interface on the Mechanism of Subvisible Particle Formation Caused by Mechanical Agitation for an IgG1 mAb

Ghazvini, Saba, Kalonia, Cavan, Volkin, David B., Dhar, Prajnaparamita

Journal:

Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 3.84 MB

english, 2016

21

High-Resolution Epitope Positioning of a Large Collection of Neutralizing and Non-Neutralizing Single Domain Antibodies on Ricin Toxin's Enzymatic and Binding Subunits

Vance, David J., Tremblay, Jacqueline M., Rong, Yinghui, Angalakurthi, Siva Krishna, Volkin, David B., Middaugh, C. Russell, Weis, David D., Shoemaker, Charles B., Mantis, Nicholas J.

Journal:

Clinical and Vaccine Immunology

Year:

2017

Language:

english

File:

PDF, 4.52 MB

english, 2017

22

Analytical Comparability Assessments of Five Recombinant CRM 197 Proteins from Different Manufacturers and Expression Systems

Hickey, John M., Toprani, Vishal M., Kaur, Kawaljit, Mishra, Ravi P.N., Goel, Akshay, Oganesyan, Natalia, Lees, Andrew, Sitrin, Robert, Joshi, Sangeeta B., Volkin, David B.

Journal:

Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 4.57 MB

english, 2018

23

Postproduction Handling and Administration of Protein Pharmaceuticals and Potential Instability Issues

Nejadnik, M. Reza, Randolph, Theodore W., Volkin, David B., Schöneich, Christian, Carpenter, John F., Crommelin, Daan J.A., Jiskoot, Wim

Journal:

Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 318 KB

english, 2018

24

Holistic process development to mitigate proteolysis of a subunit rotavirus vaccine candidate produced in Pichia pastoris by means of an acid pH pulse during fed‐batch fermentation

Velez‐Suberbie, M. Lourdes, Morris, Stephen A., Kaur, Kawaljit, Hickey, John M., Joshi, Sangeeta B., Volkin, David B., Bracewell, Daniel G., Mukhopadhyay, Tarit K.

Journal:

Biotechnology Progress

Year:

2020

Language:

english

File:

PDF, 4.73 MB

english, 2020

25

Evaluation of degradation pathways for plasmid dna in pharmaceutical formulations via accelerated stability studies

Robert K. Evans, Zheng Xu, Kathryn E. Bohannon, Bei Wang, Mark W. Bruner, David B. Volkin

Journal:

Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 350 KB

english, 2000

26

Autoreactive erythroid progenitor-T suppressor cells in the pure red cell aplasia associated with thymoma and panhypogammaglobulinemia

Kenneth F. Mangan, Robert Volkin, Alan Winkelstein

Journal:

American Journal of Hematology

Year:

1986

Language:

english

File:

PDF, 481 KB

english, 1986

27

Mechanism of thermoinactivation of immobilized glucose isomerase

David B. Volkin, Alexander M. Klibanov

Journal:

Biotechnology and Bioengineering

Year:

1989

Language:

english

File:

PDF, 782 KB

english, 1989

28

Enzyme thermoinactivation in anhydrous organic solvents

David B. Volkin, Andrea Staubli, Robert Langer, Alexander M. Klibanov

Journal:

Biotechnology and Bioengineering

Year:

1991

Language:

english

File:

PDF, 1.14 MB

english, 1991

29

Wasting of 18 S ribosomal RNA by human myeloma cells cultured in adenosine

John W. Bynum, Elliot Volkin

Journal:

Journal of Cellular Physiology

Year:

1976

Language:

english

File:

PDF, 735 KB

english, 1976

30

RNA synthesis and processing as a measure of phenotypic variability in cytodifferentiation and neoplasia

John W. Bynum, James D. Regan, Elliot Volkin

Journal:

Journal of Cellular Physiology

Year:

1977

Language:

english

File:

PDF, 905 KB

english, 1977

31

Pharmaceutical and immunological evaluation of a single-shot hepatitis B vaccine formulated with PLGA microspheres

Li Shi, Michael J. Caulfield, Rey T. Chern, Roger A. Wilson, Gautam Sanyal, David B. Volkin

Journal:

Journal of Pharmaceutical Sciences

Year:

2002

Language:

english

File:

PDF, 274 KB

english, 2002

32

Development of stable liquid formulations for adenovirus-based vaccines

Robert K. Evans, Denise K. Nawrocki, Lynne A. Isopi, Donna M. Williams, Danilo R. Casimiro, Stephen Chin, Minchun Chen, De-Min Zhu, John W. Shiver, David B. Volkin

Journal:

Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 252 KB

english, 2004

33

Stabilization of human papillomavirus virus-like particles by non-ionic surfactants

Li Shi, Gautam Sanyal, Alex Ni, Zheng Luo, Sarah Doshna, Bei Wang, Tammy L. Graham, Ning Wang, David B. Volkin

Journal:

Journal of Pharmaceutical Sciences

Year:

2005

Language:

english

File:

PDF, 436 KB

english, 2005

34

Characterization of the photodegradation of a human IgG1 monoclonal antibody formulated as a high-concentration liquid dosage form

Pei Qi, David B. Volkin, Hui Zhao, Michael L. Nedved, Robert Hughes, Ryan Bass, Sun C. Yi, Mark E. Panek, Dana Wang, Paul DalMonte, Michael D. Bond

Journal:

Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 412 KB

english, 2009

35

Evaluation of a dual-wavelength size exclusion HPLC method with improved sensitivity to detect protein aggregates and its use to better characterize degradation pathways of an IgG1 monoclonal antibody

Michael D. Bond, Mark E. Panek, Zheru Zhang, Dana Wang, Promod Mehndiratta, Hui Zhao, Keith Gunton, Alex Ni, Michael L. Nedved, Sudhir Burman, David B. Volkin

Journal:

Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 380 KB

english, 2010

36

Development of a microflow digital imaging assay to characterize protein particulates during storage of a high concentration IgG1 monoclonal antibody formulation

Klaus Wuchner, Jochen Büchler, Rene Spycher, Paul Dalmonte, David B. Volkin

Journal:

Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 260 KB

english, 2010

37

Identifying stabilizers of plasmid DNA for pharmaceutical use

Yuhong Zeng, Joshua D. Ramsey, Robert King, Michael Leviten, Ruth Mcguire, David B. Volkin, Sangeeta B. Joshi, C. Russell Middaugh

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 452 KB

english, 2011

38

Application of a high-throughput screening procedure with PEG-induced precipitation to compare relative protein solubility during formulation development with IgG1 monoclonal antibodies

Todd J. Gibson, Katie Mccarty, Iain J. Mcfadyen, Ethan Cash, Paul Dalmonte, Kenneth D. Hinds, Adam A. Dinerman, Juan C. Alvarez, David B. Volkin

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 380 KB

english, 2011

39

Multidimensional methods for the formulation of biopharmaceuticals and vaccines

Nathaniel R. Maddux, Sangeeta B. Joshi, David B. Volkin, John P. Ralston, C. Russell Middaugh

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 1.60 MB

english, 2011

40

Formulation design and high-throughput excipient selection based on structural integrity and conformational stability of dilute and highly concentrated IgG1 monoclonal antibody solutions

Akhilesh Bhambhani, Julian M. Kissmann, Sangeeta B. Joshi, David B. Volkin, Ramesh S. Kashi, C. Russell Middaugh

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 700 KB

english, 2012

41

Deamidation of polyanion-stabilized acidic fibroblast growth factor

David B. Volkin, Adeline M. Verticelli, Mark W. Bruner, Kimberly E. Marfia, P. K. Tsai, C. Russell Middaugh, Mohinder K. Sardana

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 630 KB

english, 1995

42

The co-use of retention time and bandwidth measurements in evaluations of nucleotide pools by ion-exchange chromatography

Joseph X. Khym, John W. Bynum, Elliot Volkin

Journal:

Analytical Biochemistry

Year:

1977

Language:

english

File:

PDF, 1003 KB

english, 1977

43

Characterization of subcellular poly(A) RNA populations by poly(U) Sepharose chromatography and discontinuous elution

John W. Bynum, Elliot Volkin

Journal:

Analytical Biochemistry

Year:

1980

Language:

english

File:

PDF, 866 KB

english, 1980

44

Coupled-channels method for rearrangement collisions

Howard C Volkin

Journal:

Annals of Physics

Year:

1968

Language:

english

File:

PDF, 2.08 MB

english, 1968

45

Size exclusion HPLC method for the determination of acidic fibroblast growth factor in viscous formulations

Mark W. Bruner, Joel Goldstein, C. Russell Middaugh, Marvin A. Brooks, David B. Volkin

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1997

Language:

english

File:

PDF, 505 KB

english, 1997

46

An empirical phase diagram approach to investigate conformational stability of “second-generation” functional mutants of acidic fibroblast growth factor-1

Mohammad A. Alsenaidy, Tingting Wang, Jae Hyun Kim, Sangeeta B. Joshi, Jihun Lee, Michael Blaber, David B. Volkin, C. Russell Middaugh

Journal:

Protein Science

Year:

2012

Language:

english

File:

PDF, 1.75 MB

english, 2012

47

The impact of spouse monitoring on target behavior and recorder satisfaction

Janice I. Volkin, Theodore Jacob

Journal:

Journal of Psychopathology and Behavioral Assessment

Year:

1981

Language:

english

File:

PDF, 662 KB

english, 1981

48

Degradative covalent reactions important to protein stability

David B. Volkin, Henryk Mach, C. Russell Middaugh

Journal:

Molecular Biotechnology

Year:

1997

Language:

english

File:

PDF, 1.68 MB

english, 1997

49

Size and conformational stability of the hepatitis a virus used to prepare VAQTA , a highly purified inactivated vaccine

David B. Volkin, Carl J. Burke, Kimberly E. Marfia, C. Brent Oswald, Bohdan Wolanski, C. Russell Middaugh

Journal:

Journal of Pharmaceutical Sciences

Year:

1997

Language:

english

File:

PDF, 374 KB

english, 1997

50

Nucleoside-5′-Phosphates from Ribonucleic Acid

COHN, WALDO E., VOLKIN, ELLIOT

Journal:

Year:

1951

File:

PDF, 240 KB

1951